"Midlife Coffee and Tea Drinking and the Risk of Late-Life Dementia: A Population-based CAIDE Study." Marjo H. Eskelinen, Tiia Ngandu, Jaakko Tuomilehto, Hilkka Soininen, Miia Kivipelto. Journal of Alzheimer's Disease, Vol 16, No 1, January 2009 (in press). Link.
Abstract: Caffeine stimulates central nervous system on a short term. However, the long-term impact of caffeine on cognition remains unclear. We aimed to study the association between coffee and/or tea consumption at midlife and dementia/Alzheimer's disease (AD) risk in late-life. Participants of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) study were randomly selected from the survivors of a population-based cohorts previously surveyed within the North Karelia Project and the FINMONICA study in 1972, 1977, 1982 or 1987 (midlife visit). After an average follow-up of 21 years, 1409 individuals (71%) aged 65 to 79 completed the re-examination in 1998. A total of 61 cases were identified as demented (48 with AD). Coffee drinkers at midlife had lower risk of dementia and AD later in life compared with those drinking no or only little coffee adjusted for demographic, lifestyle and vascular factors, apolipoprotein E ε4 allele and depressive symptoms. The lowest risk (65% decreased) was found in people who drank 3-5 cups per day. Tea drinking was relatively uncommon and was not associated with dementia/AD. Coffee drinking at midlife is associated with a decreased risk of dementia/AD later in life. This finding might open possibilities for prevention of dementia/AD.
Saturday, January 17, 2009
Friday, January 16, 2009
Happiness
If in your domestic life you would be supremely happy you must not forget the old adage: "The husband must not see and the wife must be blind." The Gospel Messenger, December 18, 1888.
Friday, January 02, 2009
New Year's Problem Solving
The only item that applied to me in the New Year's Day "How to fix your life in 2009" article in the Wall Street Journal was this one. And many retirees need to be on the alert--especially if you live in the the mid-west.
Problem: You work indoors, live in a cold climate and wear sunscreen to protect your skin -- and you wonder if you're getting enough vitamin D.
Solution: Have your vitamin D level checked. Experts think many people aren't getting enough these days, and that can put you at higher risk for a variety of problems, including osteoporosis, heart attacks, high blood pressure, multiple sclerosis, macular degeneration, mental illness, chronic pain and many cancers. Your doctor can check your D level with a blood test, which costs about $100 and is usually covered by insurance. Make sure the test measures 25-hydroxyvitamin D, not 1, 25-dihydroxyvitamin D. A concentration of less than 20 nanograms per milliliter is considered deficient, and more than 30 npm is healthier.
If you are low, you can boost your level with inexpensive supplements. Current U.S. guidelines call for 200 international units per day from birth through age 50; 400 IUs from 51 through 70 and 600 IUs from age 71 on. Many medical organizations now think that's too low. The American Academy of Pediatrics says children should have 400 IUs a day, and the National Osteroporsis Foundation thinks adults over age 50 should have at least 800 to 1,000.
In most of the U.S., being in the sun for at least 20 minutes a day can boost your D level nicely but also raise your risk of developing skin cancer.
—Melinda Beck
I was tested for Vit. D levels about 2 years ago as part of my annual exam, and must say, I failed miserably. I'd never heard of "low vit. D" but my wonderful internist, Dr. Bill Wulf is always ahead of me.
Problem: You work indoors, live in a cold climate and wear sunscreen to protect your skin -- and you wonder if you're getting enough vitamin D.
Solution: Have your vitamin D level checked. Experts think many people aren't getting enough these days, and that can put you at higher risk for a variety of problems, including osteoporosis, heart attacks, high blood pressure, multiple sclerosis, macular degeneration, mental illness, chronic pain and many cancers. Your doctor can check your D level with a blood test, which costs about $100 and is usually covered by insurance. Make sure the test measures 25-hydroxyvitamin D, not 1, 25-dihydroxyvitamin D. A concentration of less than 20 nanograms per milliliter is considered deficient, and more than 30 npm is healthier.
If you are low, you can boost your level with inexpensive supplements. Current U.S. guidelines call for 200 international units per day from birth through age 50; 400 IUs from 51 through 70 and 600 IUs from age 71 on. Many medical organizations now think that's too low. The American Academy of Pediatrics says children should have 400 IUs a day, and the National Osteroporsis Foundation thinks adults over age 50 should have at least 800 to 1,000.
In most of the U.S., being in the sun for at least 20 minutes a day can boost your D level nicely but also raise your risk of developing skin cancer.
—Melinda Beck
I was tested for Vit. D levels about 2 years ago as part of my annual exam, and must say, I failed miserably. I'd never heard of "low vit. D" but my wonderful internist, Dr. Bill Wulf is always ahead of me.
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